Dr Jacob did his early neurology training at the Atkinson Morley’s/St George’s Hospital in London, later moving to the West Midlands where he completed his specialist training. He did a neuromuscular / neuroimmunology fellowship under the guidance of Prof. Angela Vincent and Dr David Hilton-Jones at the University of Oxford.

His doctoral thesis was on the clinical, immunological and neurophysiological aspects of myasthenia gravis. He is currently a Consultant Neurologist at the University Hospitals of Birmingham. He is also an Honorary Senior Research Fellow at the University of Birmingham, where he looks into various neuroimmunological aspects of peripheral and central nervous system disorders.