Dr Sean Preston, Gastroenterologist

Dr Sean Preston BSc (Hons), PhD, MBBS, FRCP

Gastroenterologist

BSc (Hons), PhD, MBBS, FRCP
DrSean Preston,Gastroenterologist

Dr Preston is a recommended Gastroenterologist

GP educational film: colorectal cancer - recognising the symptoms

Upper and lower GI bleeding with Dr Sean Preston

What is Irritable Bowel Syndrome?

What is endoscopic ultrasound?

Areas of expertise

  • General gastroenterology
  • Diagnostic and theraputic endoscopy
  • Gastro-oesophageal reflux
  • Irritable bowel syndrome (IBS)
  • Barrett’s oesophagus
  • Achalasia

Recommendations for Dr Preston

These recommendations are for information purposes only. Doctors providing recommendations do so in good faith and are not responsible for clinical outcomes.

Recommended by:

  • byDr Elaine Tickle, GP

    Dr Preston is an enthusiast for delivering excellence in patient care. He is thoroughly up to date and manages patients carefully and with humour and compassion. He is my husband's physician and I am very glad he is on our team!

  • byDr Julian Stanbury Bashforth, GP

    Recommended Gastroenterologist

  • byDr George Webster, Gastroenterologist and Hepatologist

    Excellent general gastroenterologist, with a specialist interest in oesophago-gastric problems.

  • byMr Dan Wood, Urological Surgeon

    Recommended Gastroenterologist

  • by Dr Yiannis Kallis, Gastroenterologist

    Excellent clinical skills, highly competent advanced endoscopist

  • by Dr Alastair O'Brien, Gastroenterologist

    Sean is a great all-round Gastroenterologist.

  • by Mr Jonathan Wilson, Colorectal Surgeon

    Recommended Gastroenterologist

  • byDr Elaine Tickle, GP

    Dr Preston is an enthusiast for delivering excellence in patient care. He is thoroughly up to date and manages patients carefully and with humour and compassion. He is my husband's physician and I am very glad he is on our team!

  • byDr Julian Stanbury Bashforth, GP

    Recommended Gastroenterologist

  • byDr George Webster, Gastroenterologist and Hepatologist

    Excellent general gastroenterologist, with a specialist interest in oesophago-gastric problems.

  • byMr Dan Wood, Urological Surgeon

    Recommended Gastroenterologist

  • by Dr Yiannis Kallis, Gastroenterologist

    Excellent clinical skills, highly competent advanced endoscopist

  • by Dr Alastair O'Brien, Gastroenterologist

    Sean is a great all-round Gastroenterologist.

  • by Mr Jonathan Wilson, Colorectal Surgeon

    Recommended Gastroenterologist

  • Address

  • Telephone or video consultation

    Available for patients, please call to arrange, GB, W1G 8DU

  • London Digestive Health

    41 Welbeck Street, 2nd Floor, London, GB, W1G 8DU

  • The Princess Grace Hospital

    42-52 Nottingham Place, London, GB, W1U 5NY

  • Barts Health NHS Trust

    81 Commercial Rd, London, GB, E1 1RD

  • About Dr Sean Preston

    GMC number: 4230881

    Year qualified: 1995

    Place of primary qualification: University of London

    Dr Sean Preston is a Consultant Gastroenterologist and Endoscopist based at the Royal London Hospital, Barts Health, the UK's largest NHS Trust. He was featured in the 2013 Tatler Doctors Guide of Britain's top 250 consultants. His clinical practice focuses on the diagnosis and treatment of gastro-oesophageal reflux disease, Barrett's oesophagus, inflammatory bowel disease (Crohn's disease and ulcerative colitis) and irritable bowel syndrome. His endoscopic expertise relates to gastroscopy, colonoscopy and endoscopic ultrasound and he is an accredited colonoscopist for the National Bowel Cancer Screening Programme.

    Dr Preston graduated from St Mary's Hospital Medical School, Paddington in 1995. The majority of his postgraduate training was centred at Barts and the London NHS Trust, in addition to a year spent in Sydney as an Advanced Endoscopy Fellow, prior to his appointment as a consultant at Barts and the London NHS Trust. His PhD, undertaken at Cancer Research UK, London, outlined the role of stem cells in gastrointestinal cancers.

    Dr Preston has written numerous papers and book chapters on gastrointestinal cancer and continues his research in Barrett's oesophagus.

    Areas of expertise

    • General gastroenterology
    • Diagnostic and therapeutic endoscopy
    • Gastro-oesophageal reflux
    • Irritable bowel syndrome (IBS)
    • Barrett’s oesophagus
    • Achalasia
    • Heartburn
    • Eosinophilic oesophagitis
    • Oesophageal cancer
    • Colonoscopy
    • Endoscopic ultrasound
    • BRAVO pH capsule monitoring
    • Colon cancer
    • Diarrhoea
    • Constipation
    • Small intestinal bacterial overgrowth
    • Inflammatory bowel disease

    Frequently asked questions

  • What are the common symptoms that your patients tend to present with?

    The most common symptoms my patients have are abdominal pain, bloating and heartburn. These can signify serious underlying disease, but can equally be very straightforward problems to solve.

    The gastrointestinal tract has the potential to cause many varied symptoms, so it's important to identify the cause as soon as possible.

  • What are the treatments that you're able to offer your patients?

    The treatment is very pathology and patient-specific and it's very important to treat any underlying problems in a holistic manner. These can either be with lifestyle changes, medications, complex endoscopic therapies, dietary manipulation or hypnotherapy. I'm lucky enough to work in a group that can provide all of these.

  • What are your areas of sub-specialist interest?

    My main areas of subspecialist interests are endoscopic, both the diagnosis and treatment of pre-malignant and cancerous pathology in the oesophagus, stomach, pancreas and colon.

  • Professional memberships

    Articles by Dr Sean Preston

    Oxidative stress and the ovary

    Luteinizing hormone depletes ascorbic acid in preovulatory follicles

    Antioxidants reversibly inhibit the spontaneous resumption of meiosis

    Eicosatetraynoic and eicosatriynoic acids, lipoxygenase inhibitors, block meiosis via antioxidant action.

    Hormone induction of ascorbic acid transport in immature granulosa cells

    Oocyte maturation is regulated by modulation of the action of FSH in cumulus cells

    Luteolytic actions of peroxide in rat ovarian cells

    Transport and selective utilization of adenosine as a prosubstrate for luteinizing hormone-sensitive adenylate cyclase in the luteal cell

    The antigonadotropic action of prostaglandin F2 alpha is not mediated by elevated cytosolic calcium levels in rat luteal cells.

    Adenosine reverses calcium-dependent inhibition of follicle-stimulating hormone action and induction of maturation in cumulus-enclosed rat oocytes

    Other specialists recommended by Dr Preston

  • Dr Peter Irving, Gastroenterologist and General Internal Medicine

    Dr Peter Irving is a world-class IBD physician.

  • Prof. Sina Dorudi, Colorectal Surgeon

    Prof. Sina Dorudi is an excellent upper GI surgeon.

  • Dr Yiannis Kallis, Gastroenterologist

    Dr Yiannis Kallis is a fantastic hepatologist